![]() Drug interactions with grapefruit juice.Grapefruits and drugs: when is statistically significant clinically significant?. Relationship between time of intake of grapefruit juice and its effect on pharmacokinetics and pharmacodynamics of felodipine in healthy subjects. Lundahl J, Regardh CG, Edgar B, Johnsson G.Bailey DG, Malcolm J, Arnold O, Spence JD.Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression. ![]()
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